peptide 257 OVA (257-264 - Peptidelist OVA (257-264 Understanding Peptide 257: A Deep Dive into the OVA (257-264) Epitope

Peptidelist The term "peptide 257" often leads researchers and scientists to a specific and highly studied molecule: the OVA Peptide (257-264)SIINFEKL sequence.OVA Peptide (257-264) is a fragment of the OVA protein that stimulates an antibody response. It has been shown to activate various types .... This peptide is a crucial component in immunological research, particularly in understanding T-cell responses and vaccine development.OVA Peptide 257-264 | OVA polypeptide epitope | CAS NO. Its significance lies in its role as a class I (Kb)-restricted peptide epitope of OVA, a fragment derived from ovalbumin, the major protein found in egg whites.The 25-D1.16 monoclonal antibody reacts with the ovalbumin-derivedpeptideSIINFEKL bound to H-2Kb of MHC class I, but not with unbound H-2Kb. This article will delve into the intricacies of peptide 257, exploring its structure, function, and applications, drawing upon information from scientific literature and commercial suppliersOVA 257-264 (SIINFEKL) is a well-characterized, immunodominant epitope derived from chicken ovalbumin protein (Uniprot P01012)..

At its core, peptide 257 refers to a specific sequence of amino acids within the ovalbumin protein. This particular segment, spanning from amino acid 257 to 264, is known by its sequence SIINFEKL. It is an octameric peptide, meaning it is composed of eight amino acids linked together by peptide bonds. The precise sequence and its presentation by the immune system make it a valuable tool for studying immune responsesOVA Peptide 257-264 2TFA.

The primary function and significance of OVA Peptide (257-264) stem from its interaction with the immune system's major histocompatibility complex (MHC) molecules. Specifically, it is recognized as a class I (Kb)-restricted peptide epitope.OVA (257-264) (H-2Kb) | 1 mg | EP01994_1 This means that it is presented by the Class I MHC molecule, H-2Kb, on the surface of cells2025年2月17日—这是一种八聚体短肽，属于线性结构，通过肽键连接八个氨基酸。分子整体存在一定的空间构象，能够与MHC I 类分子H-2Kb 的特定部位进行特异性结合，结合区域主要 .... This presentation is a critical step in the adaptive immune response, signaling to cytotoxic T lymphocytes (CTLs), also known as CD8+ T cells, that the cell is either infected or abnormalOVA Peptide (257-264) | PEPTIDE INSTITUTE, INC.. The stimulation of these CD8+ cells and their cytotoxic T lymphocyte response is a key area of investigation when using this peptide.

The OVA Peptide (257-264) is widely used in experimental immunology as a model antigen. Its well-defined nature and immunogenicity make it ideal for a variety of research purposes.OVA Peptide(257-264) 是OVA 的I 类(Kb)-限制性肽表位，其中OVA 是一种来自卵清蛋白的八聚体肽，由I 类MHC 分子H-2Kb 所呈递。 For instance, it is frequently employed to test new adjuvant in immunotherapeutic vaccine development. Adjuvants are substances added to vaccines to enhance the immune response, and the OVA 257-264 model allows researchers to rigorously assess the efficacy of new adjuvant formulations. Furthermore, its ability to stimulate a robust immune response has led to its investigation in the context of immunotherapeutic vaccine development.

The availability of peptide 257 is widespread through various scientific suppliers.OVA 257-264 scrambled (FILKSINE) Companies offer Research-grade Ova 257 264 Peptide for laboratory use, often specifying purity levels and forms such as OVA Peptide(257-264) TFA. The "TFA" in the name refers to trifluoroacetic acid, a common counterion used during peptide synthesis and purification, ensuring stability and purity.OVA Peptide (257-264) | 138831-86-4 | POV-3659-PI These suppliers provide detailed information, including CAS numbers (eOVA 257-264 (SIINFEKL) is a well-characterized, immunodominant epitope derived from chicken ovalbumin protein (Uniprot P01012)..g., CAS NO. 1262751-08-5), chemical structures, and molecular formulas (e.g., C45H74N10O13 as listed for Ova peptide (257-264) on PubChem).

Beyond its direct use in immune stimulation, the OVA Peptide (257-264) is also studied for its structural properties.This is aclass I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb. It can form a stable hydrogel, and its linear structure, formed by the linkage of eight amino acids via peptide bonds, contributes to its specific binding to MHC moleculesOVA Peptide 257-264 2TFA. The precise spatial arrangement of the amino acids in the OVA [257-264] Peptide allows for specific binding to the H-2Kb molecule, a characteristic that can be further probed using specific antibodies like the 25-D1.16 monoclonal antibody, which reacts with the ovalbumin-derived peptide SIINFEKL bound to H-2Kb.

While the primary focus of peptide 257 is in immunological research, the broader concept of peptides extends into other fields, such as skincare. However, the context of "peptide 257" overwhelmingly points towards its immunological role. When searching for related terms, one might encounter peptide catalogs, peptide shops online, and discussions about cell peptides or bulk peptides online. These broader searches highlight the diverse applications and commercial availability of peptides in general, but the specific query for "peptide 257" narrows the focus to the OVA (257-264) epitope.

In summary, peptide 257, specifically the OVA Peptide (257-264), is a well-characterized and indispensable tool in immunology. Its role as a class I (Kb)-restricted peptide epitope of OVA, presented by the H-2Kb molecule, makes it crucial for studying T-cell mediated immunity, vaccine development, and understanding antigen presentation.OVA Peptideis a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC molecule, H-2Kb. The availability of OVA Peptide 257-264 2TFA and other forms from various suppliers underscores its importance in scientific research. While the term "peptide" has broader applications, "peptide 257" is unequivocally linked to this specific, immunologically significant fragment of ovalbuminThe 25-D1.16 monoclonal antibody reacts with the ovalbumin-derivedpeptideSIINFEKL bound to H-2Kb of MHC class I, but not with unbound H-2Kb..