peptide 137 Api137 TFA is an antimicrobial peptide - Api137 MOBKL3 peptide Unraveling the Significance of Peptide 137: From Antimicrobial Action to Biochemical Research

Peptide157 The term "peptide 137" encompasses a diverse range of molecules, each with unique properties and applicationsHIV-1 GAG Protein P24 (137-154) Peptide. NOV-PE-89131. Axxora Marketplace. Already have an account? Login to get your Account price. Overview. While the specific numerical designation might seem arbitrary, it often refers to a particular sequence or fragment within a larger protein or a synthetically designed molecule for specific research purposes. This exploration delves into the known applications and characteristics associated with peptides identified by the number 137, focusing on their roles in antimicrobial activity, biochemical assays, and potential therapeutic avenues.

A prominent example within the "peptide 137" landscape is Api137, a proline-rich antimicrobial peptide. Research has demonstrated that Api137 is an antimicrobial peptide that exhibits potent activity against bacteria by interfering with essential cellular processesApi137 is an antimicrobial peptidethat interferes with bacterial growth by inhibiting translation. Api137 inhibits protein synthesis by trapping of release .... Specifically, Api137 inhibits protein expression in bacteria through a distinct mechanism. It binds to both the ribosomal polypeptide exit tunnel and the release factor (RF), effectively arresting translation.Five Types of Skin-Repairing Peptides - Prospector Knowledge Center This mechanism of action is crucial for its bactericidal properties. Studies have also shown that Api137 mediates killing of K. pneumoniae in porcine blood ex vivo, highlighting its potential for combating bacterial infections. Furthermore, Api137 TFA is an antimicrobial peptide with similar translational inhibitory effects. The disruption of large ribosomal subunit assembly is another noted effect of Api137, underscoring its impact on bacterial protein synthesis.

Beyond antimicrobial applications, the number 137 appears in various contexts within biochemical research. For instance, PEP-137 is an 18 amino acid synthetic peptide derived from the human RanBP2 protein.This biotinylated peptidecontains the residues surrounding Ser137 of PLK. The serine residue in the peptide has been chemically phosphorylated in the ... Such peptides are often synthesized to study protein-protein interactions or as tools for specific biochemical assays.A synthetic peptide corresponding to residues 137 to 157 ... In the realm of kinase research, peptides like Phospho-PLK (Ser137) Biotinylated Peptide and ULIGHT-PLK (SER 137) PEPTIDE, LQC are utilized.The proline-rich antimicrobial peptide Api137 disrupts ... These are designed to contain the residues surrounding Ser137 of PLK, a critical phosphorylation sitePhospho-PLK (Ser137) Biotinylated Peptide. These peptides serve as substrates in TR-FRET biochemical kinase assays, allowing researchers to investigate the activity and regulation of specific kinasesBombinin-Like Peptide (137-144) / Octapeptide 2. Similarly, peptides like PLK (Ser137) Biotinylated Peptide #1300 are generated for use in heterogeneous or other assay formats, providing valuable tools for studying phosphorylation events.

The "137" designation also appears in the context of specific protein fragments and immunogenic peptidesStructure of EMI-137. Peptide sequence. The HIV-1 GAG Protein P24 (137-154) Peptide and its synonym HIV-1 gag Protein p24 (137-154) represent specific segments of the HIV-1 GAG protein, often used in immunological studies or for developing diagnostic tools. Another example is the NY-ESO-1 (123-137) peptide, which represents an epitope of tumor cells and is relevant in cancer immunology research. These high quality epitope peptides are crucial for antigen-specific stimulation of T-cells in various assays.

Furthermore, specific peptide sequences are identified by their residue numbers, such as the HA-1 RhoGAP45 137-145, VLRDDLLEA and HA-1 137-145 His139 (HLA-A*02:01) (VLHDDLLEA) peptides. These are designed for T-cell stimulation assays, including ELISPOT and intracellular cytokine staining (ICS)Definition of peptide - NCI Dictionary of Cancer Terms. The MOBKL3 peptide, corresponding to amino acids 137-151 of the MOBKL3 protein, is another example of a synthetic peptide representing a specific protein region for research.

The number 137 can also be associated with specific chemical compounds and formulations. BP Lipid 137 is an ionizable amino lipid with ester linkages, potentially used in drug delivery systems. While not a peptide itself, its designation might relate to a specific formulation or component within a larger research context.

In the therapeutic domain, AC137 (pramlintide) is a 37-residue peptide analogue of amylin that has been studied as an adjunct antihyperglycemic agent. While not directly "peptide 137," its numerical designation in a therapeutic context highlights the importance of precise peptide sequencingA synthetic peptide corresponding to residues 137 to 157 ....

The extraction and characterization of these diverse peptides often involve sophisticated techniques. For example, easy radiosynthesis, high stability in vitro and in vivo are desirable characteristics for radiolabeled peptides used in imaging or targeted therapy. The Molecular Weight: 945.02 of the Bombinin-Like Peptide (137-144) is a fundamental parameter for its identification and characterization.

In summary, "peptide 137" is a broad identifier that encompasses molecules with significant roles in antimicrobial research, biochemical assays, and immunological studiesGPIP137 Blocking Peptide. From the potent translational inhibition by Api137 to the specific phosphorylation studies involving PLK (Ser137) peptides and the immunological relevance of fragments like HIV-1 GAG Protein P24 (137-154) Peptide, these numbered peptides are invaluable tools for scientific advancement, offering insights into fundamental biological processes and potential avenues for therapeutic intervention. The existence of related searches such as Api137 TFA and Api137 mediates killing of K. pneumoniae in porcine blood further emphasizes the focused research interest surrounding this specific antimicrobial peptide.